Indian J Physiol Pharmacol. Oct;45(4) In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves. Singh B(1). Request PDF on ResearchGate | Hepatoprotective activity of Eclipta alba Hassk. against paracetamol induced hepatocellular damage in mice | The effect of. The hepatoprotective activity of different extracts of whole plant Eclipta alba was investigated against CCl4 induced hepatic damage inmale albino rat.

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Hepatoprotective activity of Eclipta alba against carbon tetrachloride-induced hepatotoxicity in albino rats. Serum was prepared from the collected blood and subjected to biochemical estimation of different parameters like aspartate aminotransferase ASTalanine aminotransferase ALTalkaline phosphatase ALPtotal lipid, triglceride, phosphatase and cholesterol.

User Username Password Remember me. Email this article Login required. After paraffin embedding block, were stained with Haemotoxylin and Eosin and examined under microscope. Animals were kept starved over night on 90 th day. Chandra T, Sadique J.

In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

A few photomicrographs of representative types were also taken. Indian J Biochem Biophys. The liver tissue was dissected by blotting of the blood washed in saline. The results of the study confirmed the hepatoprotective activity of aqueous extracts of E. On the next day the blood was collected by making an incession by jugular hepatoprogective to collect the blood.

Antioxidant activity of combined ethanolic extract of Eclipta alba and Piper longum Linn. All the group were given fresh food daily at Hepatoprotective activity of Cleome actkvity Linn. Total biochemical parameters was recorded in the present study. Suresh Kumar and Mishra have also reported hepatoprotective effect of Pergularia demia ethanol extract. Hepatoprotective effect of biherbal ethanolic extract against paracetamol-induced hepatic damage in albino rats.


Development and characterization of phyto-vesicles ecliptta wedelolactone for hepatoprotective activity. Biomed Pharmacol J ;1 1. Thus, it is quite clear that, total lipid, cholesterol and phospholipids were found to be increased against the control group Ist.

Indian J Exp Biol. J Complement Integr Med.

Cholesterol value came to be nearer to the control group of animals. Indian J Physiol Pharmacol. Keywords Carbon tetrachloride, Hepatoprotective activity, Eclipta alba, Silymarin.

Protective effect of picroliv, active constituent of Picrorhiza kurrooa, against oxytetracycline induced hepatic damage. The detail phytochemistry of the active hepatoprotective principles is still awaited.

Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats. A new receipt for liver injury. Evaluation of hepatoprotective activity of Cleome viscosa Linn. However, the dose adjustments may be necessary to optimize the similar hepatoprotective efficacy in clinical settings. One way analysis of variance ANOVA followed by Scheffes test was applied for determinig the statistical significance of difference in enzymes, protein and lipids levels between different group.

Despite the tremendous scientific advancement in the field of gastroenterology over the recent years, there is not even a single effective allopathic medication available for the treatment of liver disorders. This work is licensed under a Creative Commons Attribution 4.

A preliminary phytochemical screening was carried out for the extracts employing the standard procedure oof reveal the presene of alkaloids, steroids, terpenes, flavonoid, saponins, tennins, glycosides, carbohydrates and proteins. Hepatoprotective activity of methanol extract of Amaranthus caudatus Linn. Another gm of the powdered plant material was decocted in a ml of water.


Hepatoprotective activity of Indian Phyllanthus. They were then mechanically powdered and sieved.

In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

The extractive yield were found to be Indian herbal medicines in the treatment of liver diseases: Twenty four albino rats of wistar albino rats weighing gm were obtained from laboratory of college. This plant showed antihepatotoxic activity in assays using CCl4 galactosomine and phalloidin — induced cytotoxicity in cultured rat hepatocytes Wagner et al. In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

Hepatoprotective activity of Leptadenia reticulata stems against carbon tetrachloride-induced hepatotoxicity in rats. Similarly, level of triglyceride, total lipid and cholesterol was found to be decresed after the treatment.

As regards the total lipid the value got increased in 50 mg dose but at higher dose, it got decreased which is still much higher then the total lipid values in the control rats. Mehra and Handa, J Biochem Mol Toxicol. The level of significance was set at 0. They were given a week time to get acclimatized with the laboratory conditions.

Recent advances in herbal medicine for treatment of liver diseases. Rats were divided in to six groups of 6 rats each as follows.

KSaxena R.